John R Atack Selected Research

1- (4- chlorophenyl)- 4- piperidin- 1- yl- 1,5- dihydroimidazol- 2- one

5/2005

The benzodiazepine binding site of GABA(A) receptors as a target for the development of novel anxiolytics.

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John R Atack Research Topics

Disease

5	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 05/2006
4	Bipolar Disorder (Manic Depressive Psychosis) 07/2022 - 10/2018
4	Anxiety Disorders (Anxiety Disorder) 01/2010 - 08/2003
3	Mental Disorders (Mental Disorder) 01/2022 - 09/2009
3	Schizophrenia (Dementia Praecox) 09/2013 - 03/2008
2	Dementia (Dementias) 01/2019 - 05/2002
2	Neoplasms (Cancer) 01/2016 - 06/2014
2	Seizures (Absence Seizure) 06/2007 - 11/2006
2	Cognitive Dysfunction 02/2006 - 03/2002
1	Postpartum Depression (Post-Natal Depression) 01/2022
1	Mood Disorders (Mood Disorder) 01/2020
1	Ataxia (Dyssynergia) 01/2018
1	Catalepsy 10/2014
1	Parkinson Disease (Parkinson's Disease) 10/2014
1	Central Nervous System Diseases (CNS Diseases) 09/2013
1	Amyloid Plaque 02/2007
1	Cataract (Cataracts) 01/2006
1	Sleep Wake Disorders 01/2005
1	Epilepsy (Aura) 01/2005
1	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 08/2003
1	Down Syndrome (Down's Syndrome) 05/2002
1	Multi-Infarct Dementia (Dementia, Multi Infarct) 05/2002

Drug/Important Bio-Agent (IBA)

5	gamma-Aminobutyric Acid (GABA)IBA 02/2006 - 03/2002
4	LithiumIBA 07/2022 - 10/2018
4	myo-inositol-1 (or 4)-monophosphatase (inositol monophosphatase)IBA 10/2020 - 05/2002
3	5'-Nucleotidase (5' Nucleotidase)IBA 10/2020 - 05/2002
3	7- (1,1- dimethylethyl)- 6- (2- ethyl- 2H- 1,2,4- triazol- 3- ylmethoxy)- 3- (2- fluorophenyl)- 1,2,4- triazolo(4,3- b)pyridazineIBA 01/2018 - 01/2009
3	BenzodiazepinesIBA 01/2005 - 03/2002
2	Inositol (Myoinositol)IBA 07/2022 - 05/2002
2	EnzymesIBA 07/2022 - 05/2002
2	Apolipoprotein E4IBA 01/2019 - 01/2019
2	Diazepam (Valium)FDA LinkGeneric 01/2018 - 06/2007
2	Zolpidem (Ambien)FDA LinkGeneric 01/2018 - 06/2007
2	PoisonsIBA 01/2016 - 06/2014
2	Anti-Anxiety Agents (Anxiolytics)IBA 01/2010 - 05/2005
2	GABA-A Receptors (GABA(A) Receptor)IBA 09/2009 - 06/2007
2	Pentylenetetrazole (Metrazol)IBA 06/2007 - 11/2006
2	Peptides (Polypeptides)IBA 02/2007 - 05/2006
2	Amyloid beta-PeptidesIBA 02/2007 - 10/2006
1	Pregnanolone (Allopregnanolone)IBA 01/2022
1	NeurosteroidsIBA 01/2022
1	brexanoloneIBA 01/2022
1	Aminobutyrates (Aminobutyric Acid)IBA 03/2021
1	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 01/2020
1	Ionotropic Glutamate ReceptorsIBA 01/2020
1	Apolipoproteins E (ApoE)IBA 01/2019
1	ApolipoproteinsIBA 01/2019
1	Calbindin 1IBA 10/2018
1	Therapeutic UsesIBA 10/2018
1	Phosphatidylinositols (Phosphatidylinositol)IBA 10/2018
1	8- ethynyl- 6- (2'- pyridine)- 4H- 2,5,10b- triazabenzo(e)azulene- 3- carboxylic acid ethyl esterIBA 01/2018
1	Alprazolam (Xanax)FDA LinkGeneric 01/2018
1	Dopamine D2 Receptor AntagonistsIBA 10/2014
1	Adenosine (Adenocard)FDA LinkGeneric 10/2014
1	Dihydroxyphenylalanine (Dopa)IBA 10/2014
1	Dopamine (Intropin)FDA LinkGeneric 10/2014
1	Haloperidol (Haldol)FDA LinkGeneric 10/2014
1	Levodopa (L Dopa)FDA LinkGeneric 10/2014
1	Reserpine (Serpasil)FDA Link 10/2014
1	2- amino- 8- (2- (4- morpholinyl)ethoxy)- 4- phenyl- 5H- indeno(1,2- d)pyrimidin- 5- oneIBA 10/2014
1	Glutamic Acid (Glutamate)FDA Link 09/2013
1	Antipsychotic Agents (Antipsychotics)IBA 03/2008
1	4,2'- difluoro- 5'- (8- fluoro- 7- (1- hydroxy- 1- methylethyl)imidazo(1,2- a)pyridin- 3- yl)biphenyl- 2- carbonitrileIBA 06/2007
1	Anticonvulsants (Antiepileptic Drugs)IBA 06/2007
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 02/2007
1	L 655,708IBA 11/2006
1	Pharmaceutical PreparationsIBA 11/2006
1	TriazinesIBA 02/2006
1	PyrimidinesIBA 01/2006
1	1- (4- chlorophenyl)- 4- piperidin- 1- yl- 1,5- dihydroimidazol- 2- oneIBA 05/2005
1	ocinaplonIBA 05/2005
1	ConvulsantsIBA 03/2002
1	Chloride Channels (Chloride Channel)IBA 03/2002

Therapy/Procedure

2	Therapeutics 10/2020 - 10/2018
1	Deep Sedation 01/2018
1	Conscious Sedation 01/2018
1	Lenses 01/2006